DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study – Fiorito – – Aging Cell – Wiley Online Library

DAMA study is intentionally based on non-extreme interventions, meaning that relatively easily achievable changes in one’s lifestyle behaviors lead to a significant slowing down of biological aging biomarkers, which in turn are associated with higher longevity, lower risk of developing age-related diseases, and increased quality of life in the older age. Further, our results indicate that dietary quality and physical activity influence epigenetic aging through complementary molecular mechanisms, suggesting that their effect is potentially cumulative rather than interchangeable.

Source: DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study – Fiorito – – Aging Cell – Wiley Online Library